PSKH1 explained

Serine/threonine-protein kinase H1 is an enzyme that in humans is encoded by the PSKH1 gene.^{[1] [2]}

Interactions

PSKH1 has been shown to interact with CDC6.^[3]

Further reading

• Hanks SK . Homology probing: identification of cDNA clones encoding members of the protein-serine kinase family. . Proc. Natl. Acad. Sci. U.S.A. . 84 . 2 . 388–92 . 1987 . 2948189 . 304212 . 10.1073/pnas.84.2.388 . 1987PNAS...84..388H . free .
• Petersen BO, Lukas J, Sørensen CS, Bartek J, Helin K . Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization. . EMBO J. . 18 . 2 . 396–410 . 1999 . 9889196 . 1171134 . 10.1093/emboj/18.2.396 .
• Amarzguioui M, Brede G, Babaie E, Grotli M, Sproat B, Prydz H . Secondary structure prediction and in vitro accessibility of mRNA as tools in the selection of target sites for ribozymes. . Nucleic Acids Res. . 28 . 21 . 4113–24 . 2000 . 11058107 . 113158 . 10.1093/nar/28.21.4113 .
• Brede G, Solheim J, Tröen G, Prydz H . Characterization of PSKH1, a novel human protein serine kinase with centrosomal, golgi, and nuclear localization. . Genomics . 70 . 1 . 82–92 . 2001 . 11087665 . 10.1006/geno.2000.6365 .
• Brede G, Solheim J, Prydz H . PSKH1, a novel splice factor compartment-associated serine kinase. . Nucleic Acids Res. . 30 . 23 . 5301–9 . 2002 . 12466556 . 137962 . 10.1093/nar/gkf648 .
• Brede G, Solheim J, Stang E, Prydz H . Mutants of the protein serine kinase PSKH1 disassemble the Golgi apparatus. . Exp. Cell Res. . 291 . 2 . 299–312 . 2004 . 14644153 . 10.1016/j.yexcr.2003.07.009 .

Notes and References

1. Larsen F, Solheim J, Kristensen T, Kolstø AB, Prydz H . A tight cluster of five unrelated human genes on chromosome 16q22.1 . Hum Mol Genet . 2 . 10 . 1589–95 . Feb 1994 . 8268911 . 10.1093/hmg/2.10.1589 .
2. Web site: Entrez Gene: PSKH1 protein serine kinase H1.
3. Petersen BO, Lukas J, Sørensen CS, Bartek J, Helin K . Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization . EMBO J. . 18 . 2 . 396–410 . Jan 1999 . 9889196 . 1171134 . 10.1093/emboj/18.2.396 .