Pou class 3 homeobox 3 explained

POU class 3 homeobox 3 is a protein that in humans is encoded by the POU3F3 gene.^[1]

Function

This gene encodes a POU-domain containing protein that functions as a transcription factor. The encoded protein recognizes an octamer sequence in the DNA of target genes. This protein may play a role in development of the nervous system. [provided by RefSeq, Apr 2015].

Further reading

• Li W, Zheng J, Deng J, You Y, Wu H, Li N, Lu J, Zhou Y . Increased levels of the long intergenic non-protein coding RNA POU3F3 promote DNA methylation in esophageal squamous cell carcinoma cells . Gastroenterology . 146 . 7 . 1714–26.e5 . June 2014 . 24631494 . 10.1053/j.gastro.2014.03.002 .
• Guo H, Wu L, Yang Q, Ye M, Zhu X . Functional linc-POU3F3 is overexpressed and contributes to tumorigenesis in glioma . Gene . 554 . 1 . 114–9 . January 2015 . 25445282 . 10.1016/j.gene.2014.10.038 .

Notes and References

1. Web site: Entrez Gene: POU class 3 homeobox 3. 2018-08-13. 2020-10-20. https://web.archive.org/web/20201020235932/https://www.ncbi.nlm.nih.gov/gene/5455. live.