POLR3G explained

Polymerase (RNA) III (DNA directed) polypeptide G (32kD) is a protein that in humans is encoded by the POLR3G gene.^[1]

Further reading

• Ablasser A, Bauernfeind F, Hartmann G, Latz E, Fitzgerald KA, Hornung V . RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate . Nature Immunology . 10 . 10 . 1065–1072 . October 2009 . 19609254 . 3878616 . 10.1038/ni.1779 .
• Chiu YH, Macmillan JB, Chen ZJ . RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway . Cell . 138 . 3 . 576–591 . August 2009 . 19631370 . 2747301 . 10.1016/j.cell.2009.06.015 .
• Chantarangsu S, Mushiroda T, Mahasirimongkol S, Kiertiburanakul S, Sungkanuparph S, Manosuthi W, Tantisiriwat W, Charoenyingwattana A, Sura T, Takahashi A, Kubo M, Kamatani N, Chantratita W, Nakamura Y . 6 . Genome-wide association study identifies variations in 6p21.3 associated with nevirapine-induced rash . Clinical Infectious Diseases . 53 . 4 . 341–348 . August 2011 . 21810746 . 10.1093/cid/cir403 . free .
• Wong RC, Pollan S, Fong H, Ibrahim A, Smith EL, Ho M, Laslett AL, Donovan PJ . 6 . A novel role for an RNA polymerase III subunit POLR3G in regulating pluripotency in human embryonic stem cells . Stem Cells . 29 . 10 . 1517–1527 . October 2011 . 21898682 . 10.1002/stem.714 . 24305950 . free .
• Jang KL, Collins MK, Latchman DS . The human immunodeficiency virus tat protein increases the transcription of human Alu repeated sequences by increasing the activity of the cellular transcription factor TFIIIC . Journal of Acquired Immune Deficiency Syndromes . 5 . 11 . 1142–1147 . 1992 . 1403646 .
• Wang Z, Roeder RG . Three human RNA polymerase III-specific subunits form a subcomplex with a selective function in specific transcription initiation . Genes & Development . 11 . 10 . 1315–1326 . May 1997 . 9171375 . 10.1101/gad.11.10.1315 . free .
• Hu P, Wu S, Sun Y, Yuan CC, Kobayashi R, Myers MP, Hernandez N . Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits . Molecular and Cellular Biology . 22 . 22 . 8044–8055 . November 2002 . 12391170 . 134740 . 10.1128/MCB.22.22.8044-8055.2002 .

Notes and References

1. Web site: Entrez Gene: Polymerase (RNA) III (DNA directed) polypeptide G (32kD). 2014-04-01 .