PNPLA8 explained

Calcium-independent phospholipase A2-gamma is an enzyme that in humans is encoded by the PNPLA8 gene.^{[1] [2] [3] [4] [5]}

Further reading

• Hartley JL, Temple GF, Brasch MA . DNA Cloning Using In Vitro Site-Specific Recombination . Genome Res. . 10 . 11 . 1788–95 . 2001 . 11076863 . 10.1101/gr.143000 . 310948 .
• Wiemann S, Weil B, Wellenreuther R . Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs . Genome Res. . 11 . 3 . 422–35 . 2001 . 11230166 . 10.1101/gr.GR1547R . 311072 .
• Simpson JC, Wellenreuther R, Poustka A . Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing . EMBO Rep. . 1 . 3 . 287–92 . 2001 . 11256614 . 10.1093/embo-reports/kvd058 . 1083732 .
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Scherer SW, Cheung J, MacDonald JR . Human Chromosome 7: DNA Sequence and Biology . Science . 300 . 5620 . 767–72 . 2003 . 12690205 . 10.1126/science.1083423 . 2882961 . 2003Sci...300..767S .
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Wiemann S, Arlt D, Huber W . From ORFeome to Biology: A Functional Genomics Pipeline . Genome Res. . 14 . 10B . 2136–44 . 2004 . 15489336 . 10.1101/gr.2576704 . 528930 .
• Murakami M, Masuda S, Ueda-Semmyo K . Group VIB Ca2+-independent phospholipase A2gamma promotes cellular membrane hydrolysis and prostaglandin production in a manner distinct from other intracellular phospholipases A2 . J. Biol. Chem. . 280 . 14 . 14028–41 . 2005 . 15695510 . 10.1074/jbc.M413766200 . free .
• Mehrle A, Rosenfelder H, Schupp I . The LIFEdb database in 2006 . Nucleic Acids Res. . 34 . Database issue . D415–8 . 2006 . 16381901 . 10.1093/nar/gkj139 . 1347501 .

Notes and References

1. Mancuso DJ, Jenkins CM, Gross RW . The genomic organization, complete mRNA sequence, cloning, and expression of a novel human intracellular membrane-associated calcium-independent phospholipase A(2) . J Biol Chem . 275 . 14 . 9937–45 . May 2000 . 10744668 . 10.1074/jbc.275.14.9937 . free .
2. Tanaka H, Takeya R, Sumimoto H . A novel intracellular membrane-bound calcium-independent phospholipase A(2) . Biochem Biophys Res Commun . 272 . 2 . 320–6 . Jul 2000 . 10833412 . 10.1006/bbrc.2000.2776 .
3. Wilson PA, Gardner SD, Lambie NM, Commans SA, Crowther DJ . Characterization of the human patatin-like phospholipase family . J Lipid Res . 47 . 9 . 1940–9 . Aug 2006 . 16799181 . 10.1194/jlr.M600185-JLR200 . free .
4. Kienesberger PC, Oberer M, Lass A, Zechner R . Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions . J Lipid Res . 50 Suppl . Supplement. S63–8 . Apr 2009 . 19029121 . 2674697 . 10.1194/jlr.R800082-JLR200 . free .
5. Web site: Entrez Gene: PNPLA8 patatin-like phospholipase domain containing 8.