Polyamine-modulated factor 1 explained

Polyamine-modulated factor 1 is a protein that in humans is encoded by the PMF1 gene.^{[1] [2]}

Interactions

Polyamine-modulated factor 1 has been shown to interact with MIS12.^{[3] [4]}

Further reading

• Wang Y, Devereux W, Stewart TM, Casero RA . Characterization of the interaction between the transcription factors human polyamine modulated factor (PMF-1) and NF-E2-related factor 2 (Nrf-2) in the transcriptional regulation of the spermidine/spermine N1-acetyltransferase (SSAT) gene . The Biochemical Journal . 355 . Pt 1 . 45–9 . April 2001 . 11256947 . 1221710 . 10.1042/0264-6021:3550045 .
• Wang Y, Devereux W, Stewart TM, Casero RA . Polyamine-modulated factor 1 binds to the human homologue of the 7a subunit of the Arabidopsis COP9 signalosome: implications in gene expression . The Biochemical Journal . 366 . Pt 1 . 79–86 . August 2002 . 12020345 . 1222765 . 10.1042/BJ20020211 .
• Cheeseman IM, Niessen S, Anderson S, Hyndman F, Yates JR, Oegema K, Desai A . A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension . Genes & Development . 18 . 18 . 2255–68 . September 2004 . 15371340 . 517519 . 10.1101/gad.1234104 .
• Obuse C, Iwasaki O, Kiyomitsu T, Goshima G, Toyoda Y, Yanagida M . A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1 . Nature Cell Biology . 6 . 11 . 1135–41 . November 2004 . 15502821 . 10.1038/ncb1187 . 39408000 .
• Kline SL, Cheeseman IM, Hori T, Fukagawa T, Desai A . The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation . The Journal of Cell Biology . 173 . 1 . 9–17 . April 2006 . 16585270 . 2063780 . 10.1083/jcb.200509158 .

Notes and References

1. Wang Y, Devereux W, Stewart TM, Casero RA . Cloning and characterization of human polyamine-modulated factor-1, a transcriptional cofactor that regulates the transcription of the spermidine/spermine N(1)-acetyltransferase gene . The Journal of Biological Chemistry . 274 . 31 . 22095–101 . July 1999 . 10419538 . 10.1074/jbc.274.31.22095 . free .
2. Web site: Entrez Gene: PMF1 polyamine-modulated factor 1.
3. Cheeseman IM, Niessen S, Anderson S, Hyndman F, Yates JR, Oegema K, Desai A . A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension . Genes & Development . 18 . 18 . 2255–68 . September 2004 . 15371340 . 517519 . 10.1101/gad.1234104 .
4. Obuse C, Iwasaki O, Kiyomitsu T, Goshima G, Toyoda Y, Yanagida M . A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1 . Nature Cell Biology . 6 . 11 . 1135–41 . November 2004 . 15502821 . 10.1038/ncb1187 . 39408000 .