TRPP3 explained

Polycystic kidney disease 2-like 2 protein (PKD2L2) also known as transient receptor potential polycystic 5 (TRPP5) is a protein that in humans is encoded by the PKD2L2 gene.^[1]

TRPP5 is a member of the transient receptor potential channel family of proteins.

See also

• TRPP

Further reading

• Li Q, Liu Y, Zhao W, Chen XZ . The calcium-binding EF-hand in polycystin-L is not a domain for channel activation and ensuing inactivation. . FEBS Lett. . 516 . 1–3 . 270–8 . 2002 . 11959145 . 10.1016/S0014-5793(02)02513-9. 1812119 . free . 2002FEBSL.516..270L .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2002 . 12477932 . 139241 . 10.1073/pnas.242603899 . 2002PNAS...9916899M . free .
• Stayner C, Zhou J . Polycystin channels and kidney disease . Trends Pharmacol. Sci. . 22 . 11 . 543–6 . 2001 . 11698076 . 10.1016/S0165-6147(00)01832-0 .
• Guo L, Schreiber TH, Weremowicz S, etal . Identification and characterization of a novel polycystin family member, polycystin-L2, in mouse and human: sequence, expression, alternative splicing, and chromosomal localization . Genomics . 64 . 3 . 241–51 . 2000 . 10756092 . 10.1006/geno.2000.6131 .

Notes and References

1. Veldhuisen B, Spruit L, Dauwerse HG, Breuning MH, Peters DJ . Genes homologous to the autosomal dominant polycystic kidney disease genes (PKD1 and PKD2) . Eur. J. Hum. Genet. . 7 . 8 . 860–72 . December 1999 . 10602361 . 10.1038/sj.ejhg.5200383 . free .