PI4K2B explained

Phosphatidylinositol 4-kinase type 2-beta is an enzyme that in humans is encoded by the PI4K2B gene.^{[1] [2]}

Further reading

• Griffioen M, van der Meijden ED, Slager EH, etal . Identification of phosphatidylinositol 4-kinase type II beta as HLA class II-restricted target in graft versus leukemia reactivity. . Proc. Natl. Acad. Sci. U.S.A. . 105 . 10 . 3837–42 . 2008 . 18316730 . 10.1073/pnas.0712250105 . 2268788 . 2008PNAS..105.3837G . free .
• Jones DR, Bultsma Y, Keune WJ, etal . Nuclear PtdIns5P as a transducer of stress signaling: an in vivo role for PIP4Kbeta. . Mol. Cell . 23 . 5 . 685–95 . 2006 . 16949365 . 10.1016/j.molcel.2006.07.014 . free .
• Srivastava R, Sinha RK, Subrahmanyam G . Type II phosphatidylinositol 4-kinase beta associates with TCR-CD3 zeta chain in Jurkat cells. . Mol. Immunol. . 43 . 5 . 454–63 . 2006 . 16337488 . 10.1016/j.molimm.2005.03.009 .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Wei YJ, Sun HQ, Yamamoto M, etal . Type II phosphatidylinositol 4-kinase beta is a cytosolic and peripheral membrane protein that is recruited to the plasma membrane and activated by Rac-GTP. . J. Biol. Chem. . 277 . 48 . 46586–93 . 2003 . 12324459 . 10.1074/jbc.M206860200 . free .
• Mora S, Durham PL, Smith JR, etal . NCS-1 inhibits insulin-stimulated GLUT4 translocation in 3T3L1 adipocytes through a phosphatidylinositol 4-kinase-dependent pathway. . J. Biol. Chem. . 277 . 30 . 27494–500 . 2002 . 12011096 . 10.1074/jbc.M203669200 . free . 2445/176737 . free .
• Huang C, Handlogten ME, Miller RT . Parallel activation of phosphatidylinositol 4-kinase and phospholipase C by the extracellular calcium-sensing receptor. . J. Biol. Chem. . 277 . 23 . 20293–300 . 2002 . 11907035 . 10.1074/jbc.M200831200 . free .

Notes and References

1. Balla A, Tuymetova G, Barshishat M, Geiszt M, Balla T . Characterization of type II phosphatidylinositol 4-kinase isoforms reveals association of the enzymes with endosomal vesicular compartments . J Biol Chem . 277 . 22 . 20041–50 . May 2002 . 11923287 . 10.1074/jbc.M111807200 . free .
2. Web site: Entrez Gene: PI4K2B phosphatidylinositol 4-kinase type 2 beta.