PGM2 explained

Phosphoglucomutase-2 is an enzyme that in humans is encoded by the PGM2 gene.^{[1] [2]} PGM2 is a major isozyme in red blood cells.

Further reading

• Sparkes RS, Mohandas T, Sparkes MC, Shulkin JD . Regional localization of human phosphoglucomutase-2 locus on chromosome 4. . Exp. Cell Res. . 111 . 2 . 492–5 . 1978 . 564278 . 10.1016/0014-4827(78)90200-8 .
• Francke U, Brown S . Regional assignment of genes for phosphoglucomutase2 and peptidase S to 4pter leads to 4q21 in man. . Cytogenet. Cell Genet. . 22 . 1–6 . 401–5 . 1979 . 752511 . 10.1159/000130982 .
• Sparkes RS, Mohandas T, Sparkes MC, Shulkin JD . Human PGM2 (E.C. 2.7.5.1) mapped to 4pter leads to 4q25 . Cytogenet. Cell Genet. . 22 . 1–6 . 406–7 . 1979 . 752512 . 10.1159/000130983 .
• Wijnen LM, Grzeschik KH, Pearson PL, Meera Khan P . The human PGM-2 and its chromosomal localization in man-mouse hybrids . Hum. Genet. . 37 . 3 . 271–8 . 1977 . 885546 . 10.1007/BF00393608 . 33293909 .
• McAlpine PJ, Mohandas T, Komarnicki L, etal . Further data on the assignment of the phosphoglucomutase2 (PGM2) gene locus to chromosome 4 in man . Cytogenet. Cell Genet. . 14 . 3–6 . 368–9 . 1976 . 1192820 . 10.1159/000130386 .
• McAlpine PJ, Mohandas T, Komarnicki L, etal . Further data on the assignment of the phosphoglucomutase (PGM2) gene locus to chromosome 4 in man . Birth Defects Orig. Artic. Ser. . 11 . 3 . 198–9 . 1976 . 1203483 .
• Hopkinson DA, Harris H . Evidence for a second "structural" locus determining human phosphoglucomutase . Nature . 208 . 5008 . 410–2 . 1966 . 5885461 . 10.1038/208410a0 . 4187305 .
• Maruyama K, Sugano S . Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides . Gene . 138 . 1–2 . 171–4 . 1994 . 8125298 . 10.1016/0378-1119(94)90802-8 .
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, etal . Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library . Gene . 200 . 1–2 . 149–56 . 1997 . 9373149 . 10.1016/S0378-1119(97)00411-3 .
• Wiemann S, Weil B, Wellenreuther R, etal . Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs . Genome Res. . 11 . 3 . 422–35 . 2001 . 11230166 . 10.1101/gr.GR1547R . 311072 .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Gevaert K, Goethals M, Martens L, etal . Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides . Nat. Biotechnol. . 21 . 5 . 566–9 . 2004 . 12665801 . 10.1038/nbt810 . 23783563 .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Maliekal P, Sokolova T, Vertommen D, etal . Molecular identification of mammalian phosphopentomutase and glucose-1,6-bisphosphate synthase, two members of the alpha-D-phosphohexomutase family . J. Biol. Chem. . 282 . 44 . 31844–51 . 2007 . 17804405 . 10.1074/jbc.M706818200 . free .

Notes and References

1. Whitehouse DB, Tomkins J, Lovegrove JU, Hopkinson DA, McMillan WO . A phylogenetic approach to the identification of phosphoglucomutase genes . Mol Biol Evol . 15 . 4 . 456–62 . May 1998 . 9549096 . 10.1093/oxfordjournals.molbev.a025942.
2. Web site: Entrez Gene: PGM2 phosphoglucomutase 2.