PGK1 explained

Phosphoglycerate kinase 1 is an enzyme that in humans is encoded by the PGK1 gene.^{[1] [2] [3]}

Further reading

• Vishwanatha JK, Jindal HK, Davis RG . The role of primer recognition proteins in DNA replication: association with nuclear matrix in HeLa cells. . 101 . J. Cell Sci. . (Pt 1) . 25–34 . 1992 . 10.1242/jcs.101.1.25 . 1533225 .
• Fujii H, Kanno H, Hirono A, etal . A single amino acid substitution (157 Gly----Val) in a phosphoglycerate kinase variant (PGK Shizuoka) associated with chronic hemolysis and myoglobinuria. . Blood . 79 . 6 . 1582–5 . 1992 . 10.1182/blood.V79.6.1582.1582 . 1547346 . free .
• Maeda M, Bawle EV, Kulkarni R, etal . Molecular abnormalities of a phosphoglycerate kinase variant generated by spontaneous mutation. . Blood . 79 . 10 . 2759–62 . 1992 . 10.1182/blood.V79.10.2759.bloodjournal79102759 . 2024-04-08 . 1586722 . free .
• Dawson SJ, White LA . Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin. . J. Infect. . 24 . 3 . 317–20 . 1992 . 1602151 . 10.1016/S0163-4453(05)80037-4 .
• Kumble KD, Vishwanatha JK . Immunoelectron microscopic analysis of the intracellular distribution of primer recognition proteins, annexin 2 and phosphoglycerate kinase, in normal and transformed cells. . 99 . J. Cell Sci. . (Pt 4) . 751–8 . 1992 . 4 . 10.1242/jcs.99.4.751 . 1837552 .
• Maeda M, Yoshida A . Molecular defect of a phosphoglycerate kinase variant (PGK-Matsue) associated with hemolytic anemia: Leu----Pro substitution caused by T/A----C/G transition in exon 3. . Blood . 77 . 6 . 1348–52 . 1991 . 10.1182/blood.V77.6.1348.1348 . 2001457 . free .
• Jindal HK, Vishwanatha JK . Functional identity of a primer recognition protein as phosphoglycerate kinase. . J. Biol. Chem. . 265 . 12 . 6540–3 . 1990 . 10.1016/S0021-9258(19)39179-3 . 2324090 . free .
• Johnson P, Friedmann T . Limited bidirectional activity of two housekeeping gene promoters: human HPRT and PGK. . Gene . 88 . 2 . 207–13 . 1990 . 2347494 . 10.1016/0378-1119(90)90033-N .
• Pfeifer GP, Steigerwald SD, Mueller PR, etal . Genomic sequencing and methylation analysis by ligation mediated PCR. . Science . 246 . 4931 . 810–3 . 1989 . 2814502 . 10.1126/science.2814502 . 1989Sci...246..810P .
• Michelson AM, Blake CC, Evans ST, Orkin SH . Structure of the human phosphoglycerate kinase gene and the intron-mediated evolution and dispersal of the nucleotide-binding domain. . Proc. Natl. Acad. Sci. U.S.A. . 82 . 20 . 6965–9 . 1985 . 2995995 . 10.1073/pnas.82.20.6965 . 391290 . 1985PNAS...82.6965M . free .
• McCarrey JR, Thomas K . Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene. . Nature . 326 . 6112 . 501–5 . 1987 . 3453121 . 10.1038/326501a0 . 1987Natur.326..501M . 4353366 .
• Fujii H, Yoshida A . Molecular abnormality of phosphoglycerate kinase-Uppsala associated with chronic nonspherocytic hemolytic anemia. . Proc. Natl. Acad. Sci. U.S.A. . 77 . 9 . 5461–5 . 1981 . 6933565 . 10.1073/pnas.77.9.5461 . 350080 . free .
• Fujii H, Chen SH, Akatsuka J, etal . Use of cultured lymphoblastoid cells for the study of abnormal enzymes: molecular abnormality of a phosphoglycerate kinase variant associated with hemolytic anemia. . Proc. Natl. Acad. Sci. U.S.A. . 78 . 4 . 2587–90 . 1981 . 6941312 . 10.1073/pnas.78.4.2587 . 319394 . 1981PNAS...78.2587F . free .
• Huang IY, Welch CD, Yoshida A . Complete amino acid sequence of human phosphoglycerate kinase. Cyanogen bromide peptides and complete amino acid sequence. . J. Biol. Chem. . 255 . 13 . 6412–20 . 1980 . 10.1016/S0021-9258(18)43754-4 . 7391027 . free .
• Fujii H, Krietsch WK, Yoshida A . A single amino acid substitution (Asp leads to Asn) in a phosphoglycerate kinase variant (PGK München) associated with enzyme deficiency. . J. Biol. Chem. . 255 . 13 . 6421–3 . 1980 . 10.1016/S0021-9258(18)43755-6 . 7391028 . free .
• Huang IY, Fujii H, Yoshida A . Structure and function of normal and variant human phosphoglycerate kinase. . Hemoglobin . 4 . 5–6 . 601–9 . 1981 . 7440217 . 10.3109/03630268008997730 .
• Kato S, Sekine S, Oh SW, etal . Construction of a human full-length cDNA bank. . Gene . 150 . 2 . 243–50 . 1995 . 7821789 . 10.1016/0378-1119(94)90433-2 .
• Hershkovitz M, Riggs AD . Metaphase chromosome analysis by ligation-mediated PCR: heritable chromatin structure and a comparison of active and inactive X chromosomes. . Proc. Natl. Acad. Sci. U.S.A. . 92 . 6 . 2379–83 . 1995 . 7892275 . 10.1073/pnas.92.6.2379 . 42487 . 1995PNAS...92.2379H . free .

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Phosphoglycerate kinase 1

Notes and References

1. Michelson AM, Markham AF, Orkin SH . Isolation and DNA sequence of a full-length cDNA clone for human X chromosome-encoded phosphoglycerate kinase . Proc Natl Acad Sci U S A . 80 . 2 . 472–6 . May 1983 . 6188151 . 393400 . 10.1073/pnas.80.2.472 . 1983PNAS...80..472M . free .
2. Singer-Sam J, Keith DH, Tani K, Simmer RL, Shively L, Lindsay S, Yoshida A, Riggs AD . Sequence of the promoter region of the gene for human X-linked 3-phosphoglycerate kinase] . Gene . 32 . 3 . 409–17 . May 1985 . 6099325 . 10.1016/0378-1119(84)90016-7 .
3. Web site: Entrez Gene: PGK1 phosphoglycerate kinase 1.