PDE1C explained

Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C is an enzyme that in humans is encoded by the PDE1C gene.^{[1] [2]}

Further reading

• Vandeput F, Wolda SL, Krall J, etal . Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes. . J. Biol. Chem. . 282 . 45 . 32749–57 . 2007 . 17726023 . 10.1074/jbc.M703173200 . free .
• Dolci S, Belmonte A, Santone R, etal . Subcellular localization and regulation of type-1C and type-5 phosphodiesterases. . Biochem. Biophys. Res. Commun. . 341 . 3 . 837–46 . 2006 . 16455054 . 10.1016/j.bbrc.2006.01.035 . 11573/979485 .
• Ota T, Suzuki Y, Nishikawa T, etal . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . free .
• Hillier LW, Fulton RS, Fulton LA, etal . The DNA sequence of human chromosome 7. . Nature . 424 . 6945 . 157–64 . 2003 . 12853948 . 10.1038/nature01782 . 2003Natur.424..157H . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Rybalkin SD, Rybalkina I, Beavo JA, Bornfeldt KE . Cyclic nucleotide phosphodiesterase 1C promotes human arterial smooth muscle cell proliferation. . Circ. Res. . 90 . 2 . 151–7 . 2002 . 11834707 . 10.1161/hh0202.104108 . free .
• Yan C, Zhao AZ, Sonnenburg WK, Beavo JA . Stage and cell-specific expression of calmodulin-dependent phosphodiesterases in mouse testis. . Biol. Reprod. . 64 . 6 . 1746–54 . 2001 . 11369604 . 10.1095/biolreprod64.6.1746 . free .
• Zauli G, Milani D, Mirandola P, etal . HIV-1 Tat protein down-regulates CREB transcription factor expression in PC12 neuronal cells through a phosphatidylinositol 3-kinase/AKT/cyclic nucleoside phosphodiesterase pathway. . FASEB J. . 15 . 2 . 483–91 . 2001 . 11156964 . 10.1096/fj.00-0354com . free . 26315564 .

Notes and References

1. Loughney K, Martins TJ, Harris EA, Sadhu K, Hicks JB, Sonnenburg WK, Beavo JA, Ferguson K . Isolation and characterization of cDNAs corresponding to two human calcium, calmodulin-regulated, 3',5'-cyclic nucleotide phosphodiesterases . J Biol Chem . 271 . 2 . 796–806 . Feb 1996 . 8557689 . 10.1074/jbc.271.2.796 . free .
2. Web site: Entrez Gene: PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa.