Ozolinone Explained

Ozolinone is a loop diuretic which was never marketed.^{[1] [2] [3]}

It is an active metabolite of etozoline.^[2]

See also

• Etozoline — a prodrug of ozolinone

Notes and References

1. Book: Dictionary of organic compounds . Chapman & Hall . London . 1996 . 0-412-54090-8 .
2. Greven J, Heidenreich O . Effects of ozolinone, a diuretic active metabolite of etozoline, on renal function. I. Clearance studies in dogs . Naunyn-Schmiedeberg's Archives of Pharmacology . 304 . 3 . 283–7 . October 1978 . 714186 . 10.1007/bf00507970. 20878253 .
3. Greven J, Beckers M, Defrain W, Meywald K, Heidenreich O . Studies with the optically active isomers of the new diuretic drug ozolinone. II. Inhibition by d-ozolinone of furosemide-induced diuresis . Pflügers Archiv: European Journal of Physiology . 384 . 1 . 61–4 . March 1980 . 7189867 . 10.1007/bf00589515. 13461213 .