Oxotremorine Explained

Oxotremorine is a drug that acts as a selective muscarinic acetylcholine receptor agonist.[1]

Oxotremorine produces ataxia, tremor and spasticity, similar to those symptoms seen in Parkinsonism, and has thus become a research tool in experimental studies aimed at determining more effective anti-Parkinsonian drugs.[2]

Oxotremorine also produces antipsychotic effects.[3]

See also

Notes and References

  1. Tang C, Castoldi AF, Costa LG . Effects of the muscarinic agonist oxotremorine on membrane fluidity in rat lymphocytes . Biochemistry and Molecular Biology International . 29 . 6 . 1047–54 . April 1993 . 8330013 . .
  2. Book: Craig CR, Stitzel RE . Modern Pharmacology with Clinical Applications . 2004 . Lippincott Williams & Wilkins . 978-0-7817-3762-3 .
  3. Maehara S, Hikichi H, Satow A, Okuda S, Ohta H . Antipsychotic property of a muscarinic receptor agonist in animal models for schizophrenia . Pharmacology, Biochemistry, and Behavior . 91 . 1 . 140–9 . November 2008 . 18651995 . 10.1016/j.pbb.2008.06.023 . 12225821 . .

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