Oxomemazine/guaifenesin explained

Type:combo
Component1:Oxomemazine
Class1:H1 receptor antagonist
(antihistamine)
Component2:Guaifenesin
Class2:expectorant
Tradename:Toplexil and others
Routes Of Administration:Oral
Cas Number:153445-20-6
Atc Prefix:none

Oxomemazine/guaifenesin is a sedative antihistamine plus expectorant.[1] [2] It is a combination of oxomemazine and guaifenesin.

It is sold under a variety of brand names including Toplexil by Aventis. It is sold over the counter in France, Morocco, Egypt, Algeria, South Korea and the UAE. The oxomemazine ingredient (antihistamine) is not approved by the U.S. Food and Drug Administration (FDA), either for over the counter or prescription use. It is sold in France as cough syrup. French travelers also use it as a sleeping aid for long flights.

Notes and References

  1. https://www.drugs.com/international/oxomemazine.html Oxomemazine
  2. https://www.drugs.com/international/toplexil.html Toplexil