Oxime V Explained

Oxime V is a chemical compound that has been studied as a potential sweetener. Oxime V was first reported in 1976 as a synthetic analog of the artificial sweetener perillartine.^[1] It is about 450 times as sweet as sucrose and is more water-soluble than perillartine.^[2] Its metabolism and toxicology have been investigated,^[3] and it has been found to have promising properties,^[2] but it is not currently marketed.

In 2022, oxime V was identified in citrus.^{[4] [5]}

Notes and References

1. 10.1126/science.959816 . Potential New Artificial Sweetener from Study of Structure-Taste Relationships . 1976 . Acton . E. M. . Stone . H. . Science . 193 . 4253 . 584–586 . 959816 . 1976Sci...193..584A .
2. Book: Lyn O'Brien-Nabors . Alternative Sweeteners . 3rd . 2001 . 0-8247-0437-1 . 222 . A. Douglas Kinghorn and Cesar M. Comadre . Chapter 12. Less Common High-Potency Sweeteners .
3. 10.3109/01480548509038645 . Metabolic and Toxicologic Study of an Artificial Sweetener, Oxime V . 1985 . Hitoma . C. . Acton . E. M. . Degraw . J. I. . Thomas . D. W. . Drug and Chemical Toxicology . 8 . 4 . 195–206 . 3841048 .
4. 10.1021/acs.jafc.2c03515 . Natural Sweeteners and Sweetness-Enhancing Compounds Identified in Citrus Using an Efficient Metabolomics-Based Screening Strategy . 2022 . Wang . Zhixin . Gmitter . Frederick G. . Grosser . Jude W. . Wang . Yu . Journal of Agricultural and Food Chemistry . 70 . 34 . 10593–10603 . 35980814 . 251645690 .
5. Web site: Researchers find new sugar substitutes in citrus that could change food and beverage industry . September 20, 2022 . Science Daily .