Oxbow orthohantavirus explained

Oxbow virus (OXBV) is a single-stranded, enveloped, negative-sense RNA orthohantavirus.^[1]

Natural reservoir

Oxbow virus was isolated from an American shrew mole (Neurotrichus gibbsii), captured in Gresham, Oregon, in September 2003.

Virology

The genome of the Oxbow virus along the full length of the S, M, and partial L-segment nucleotide and amino acid sequences show a low sequence similarity to rodent-borne hantaviruses. Phylogenetic analysis demonstrated that Oxbow virus and Asama virus are related to soricine shrew-borne hantaviruses found in North America, Europe, and Asia. This suggests both these viruses evolved with cross-species transmission.

See also

• Hantavirus pulmonary syndrome
• Hantavirus hemorrhagic fever with renal syndrome
• Cross-species transmission

External links

• CDC's Hantavirus Technical Information Index page
• Viralzone: Hantavirus
• Virus Pathogen Database and Analysis Resource (ViPR): Hantaviridae
• Occurrences and deaths in North and South America

Notes and References

1. Kang HJ, Bennett SN, Dizney L, Sumibcay L, Arai S, Ruedas LA, Song JW, Yanagihara R.Host switch during evolution of a genetically distinct hantavirus in the American shrew mole (Neurotrichus gibbsii).Virology. 2009 May 25;388(1):8–14.