| Official Name: | Överkalix |
| Pushpin Map: | Sweden Norrbotten#Sweden |
| Pushpin Label Position: | left |
| Subdivision Type: | Country |
| Subdivision Name: | Sweden |
| Subdivision Type3: | Municipality |
| Subdivision Name3: | Överkalix Municipality |
| Subdivision Type2: | County |
| Subdivision Name2: | Norrbotten County |
| Subdivision Type1: | Province |
| Subdivision Name1: | Norrbotten |
| Area Footnotes: | [1] |
| Area Total Km2: | 1.06 |
| Population As Of: | 31 December 2010 |
| Population Total: | 975 |
| Population Density Km2: | 919 |
| Timezone: | CET |
| Utc Offset: | +1 |
| Timezone Dst: | CEST |
| Utc Offset Dst: | +2 |
| Coordinates: | 66.35°N 75°W |
Överkalix (in Swedish ˈø̂ːvɛrˌkɑːlɪks/; Finnish: Ylikainuu) is a locality and the seat of Överkalix Municipality in Norrbotten County, Sweden with 975 inhabitants in 2010.
Överkalix has a subarctic climate with significant temperature differences between the warm short summers and the long and cold winters. Its inland position close to sea level ensures Överkalix is more prone to heatwaves than other areas of Norrbotten. Its July temperatures are also due to the perpetual daylight due to its position just below the Arctic Circle. This results in July days being warmer on average than other European cities as far south as Manchester and Dublin in the British Isles. However, temperatures fall quickly once daylight diminishes, but winters are still less severe than other parts of the world at similar parallels due to mild North Atlantic air somewhat tempering cold extremes. The climate is quite dry for Scandinavia, with average annual precipitation being at 450mm.[2]
The Överkalix study (Swedish: Överkalixstudien) was a study conducted on the physiological effects of various environmental factors on transgenerational epigenetic inheritance. The study was conducted utilizing historical records, including harvests and food prices, in Överkalix, a small isolated municipality in northeast Sweden. The study was of 303 probands, 164 men and 139 women, born in 1890, 1905, or 1920, and their 1,818 children and grandchildren. 44 were still alive in 1995 when mortality follow-up stopped. Mortality risk ratios (RR) on children and grandchildren were determined based on available food supply, as indicated by historical data.
Överkalix was used as location for the Swedish films Frostbite and False Trail.