| Otto II, Duke of Brunswick-Osterode | |
| House: | House of Guelph |
| Father: | Frederick I, Duke of Brunswick-Osterode |
| Mother: | Adelaide of Anhalt-Zerbst |
| Spouse: | Schonetta of Nassau-Weilburg |
| Birth Date: | 1396 |
| Death Date: | 1452 |
Duke Otto II (or Otho) of Brunswick-Osterode (1396–1452)[1] was a son of Duke Frederick I of Brunswick-Osterode and his wife, Adelaide of Anhalt-Zerbst, or possibly Elizabeth, heiress of Homburg. He succeeded his father as duke of Brunswick-Osterode in 1421 and ruled jointly with his first cousin once removed Albert II.
Otto was married to Schonetta (or Schonela) (d. 1436),[1] a daughter of Count John I of Nassau-Weilburg. This marriage was childless.[1]