Otrhonia is an extinct genus of notoungulate, belonging to the Notostylopidae family. It lived during the Late Eocene, and its remains were discovered in South America.
This animal was approximately the size of a modern racoon, and its length may have been around 60–70 centimeters excluding the tail. The skull was 14–15 centimeters long, and the animal may have been close to 10 kilograms.
Otrhonia had a robust and square skull, characterised by its specialized dentition. As well as in some of its relatives, such as Notostylops, there was a noticeable diastema between the anterior teeth and the premolars. In Otrhonia this diastema was more elongated than in other genera, and the crown of the molars was higher (hypsodont). The first pair of upper incisors were quite large and directed downwards.
Otrhonia muehlbergi was first described in 1901 by Santiago Roth, based on a fossil found in Argentina near the Lago Musters (hence its name, derived from the lake local name, Otròn), in terrains dating from the Eocene.
Otrhonia was a notostylopid, a group of notoungulates with a curious mixture of basal and derived characteristics. Otrhonia may have been one of the more specialized forms of the family, and is also one of the latest known forms from it.
Otrhonia was a terrestrial animal, feeding on leaves and fruits. There is no animal from modern South America sharing the same dentition, but it is vaguely similar to that of the Australian koala, an arboreal animal.