| Country: | TUR |
| Type: | otoyol |
| Route: | 51 |
| Alternate Name: | Adana-Erdemli Motorway Adana-Erdemli Otoyolu |
| Established: | 1992 |
| Terminus A: | in Seyhan, Adana |
| Terminus B: | in Erdemli, Mersin |
| Junction: | |
| Length Km: | 82.3 |
| Regions: | Mediterranean |
| Provinces: | Adana, Mersin |
| Cities: | Adana, Tarsus, Mersin |
| Map: | Karte O51 TR 2015.svg |
| Previous Type: | O |
| Previous Route: | 33 |
| Next Type: | O |
| Next Route: | 52 |
Otoyol 51 (English: Motorway 51), abbreviated as O-51, aka Adana-Erdemli Otoyolu (English: Adana-Erdemli Motorway), is a toll motorway in the Mediterranean Region of Turkey, connecting the cities Adana and Mersin. The motorway is on its full length of 99km (62miles) part of international routes as of European routes E90 and E982 and Asian Highway 84.
The motorway starts from the western terminus of O-52 in Central Adana, runs westward reaching the south terminus of Pozantı-Adana Motorway O-21 northeast of Tarsus, continues southwest to Mersin bypassing it at north and terminates in Erdemli.
There are plans to extend the motorway to Silifke.
| width=100 | Province ! | width=100 | District ! | width=40 | km ! | width=40 | mi ! | width=30 | Exit ! | width=300 | Destination ! | width=200 | Notes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Adana | Yüreğir | style='background: #dcdcdc' | 0.0 | style='background: #dcdcdc' | 0.0 | K1 | Dr. Mithat Özsan Blv. | Continues as to Şanlıurfa | |||||
| Seyhan River | style='background: #dcdcdc' | 0.0 | style='background: #dcdcdc' | 0.0 | Seyhan Viaduct | ||||||||
| Seyhan/Çukurova | style='background: #dcdcdc' | style='background: #dcdcdc' | K2 | Özdemir Sabancı Blvd. — Beyazevler | |||||||||
| style='background: #dcdcdc' | style='background: #dcdcdc' | style='background: #FFDDF4' | K3 | style='background: #FFDDF4' | Mavi Blv. | style='background: #FFDDF4' | Eastbound entrance and exit | ||||||
| style='background: #dcdcdc' | style='background: #dcdcdc' | style='background: #FFDDF4' | K3 | style='background: #FFDDF4' | Kasım Yener Blvd. | style='background: #FFDDF4' | Westbound entrance and exit | ||||||
| style='background: #dcdcdc' | style='background: #dcdcdc' | style='background: #FFDDF4' | - | style='background: #FFDDF4' | Dr. Ahmet Sadık Blvd. | style='background: #FFDDF4' | Westbound exit | ||||||
| style='background: #dcdcdc' | style='background: #dcdcdc' | K4 | Öğretmenler Blvd. | ||||||||||
| style='background: #dcdcdc' | style='background: #dcdcdc' | K5 | — Karaisali | ||||||||||
| Mersin | Tarsus | style='background: #dcdcdc' | style='background: #dcdcdc' | ||||||||||
| style='background: #dcdcdc' | style='background: #dcdcdc' | style='background: #ccccff' | K19 | style='background: #ccccff' | — Ulukışla, Niğde | style='background: #ccccff' | |||||||
| style='background: #dcdcdc' | style='background: #dcdcdc' | style='background: #ccccff' | K6 | style='background: #ccccff' | — Aksaray, Ankara | style='background: #ccccff' | |||||||
| style='background: #dcdcdc' | style='background: #dcdcdc' | Berdan Viaduct | |||||||||||
| style='background: #dcdcdc' | style='background: #dcdcdc' | style='background: #ccccff' | K7 | style='background: #ccccff' | Tarsus connector — Tarsus | style='background: #ccccff' | Connector to | ||||||
| Akdeniz | style='background: #dcdcdc' | style='background: #dcdcdc' | |||||||||||
| style='background: #dcdcdc' | style='background: #dcdcdc' | K8 | 151st St. — Mersin | Connector to | |||||||||
| Toroslar | style='background: #dcdcdc' | style='background: #dcdcdc' | K9 | — Mersin, Gözne | |||||||||
| Yenişehir | style='background: #dcdcdc' | style='background: #dcdcdc' | K10 | Pamuklu Ave. — Mersin Arena | |||||||||
| Mezitli | style='background: #dcdcdc' | style='background: #dcdcdc' | K11 | Vatan Ave. — Kuyuluk | |||||||||
| Erdemli | style='background: #dcdcdc' | style='background: #dcdcdc' | K12 | — Anamur, Antalya | |||||||||