| Osse | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Osse (Doubs).svg |
| Coordinates: | 47.2678°N 6.2136°W |
| Insee: | 25437 |
| Postal Code: | 25360 |
| Arrondissement: | Besançon |
| Canton: | Baume-les-Dames |
| Mayor: | Charles Piquard[1] |
| Term: | 2020 - 2026 |
| Elevation Min M: | 392 |
| Elevation Max M: | 565 |
| Area Km2: | 8.21 |
Osse (in French pronounced as /ɔs/) is a commune in the Doubs department in the Bourgogne-Franche-Comté region in eastern France.