| Ospenke | |
| Subdivision Type1: | Country |
| Subdivision Name1: | Germany |
| Subdivision Type2: | State |
| Subdivision Name2: | Lower Saxony |
| Length: | [1] |
| Source1 Location: | east of Osterode |
| Source1 Elevation: | ca. |
| Mouth Location: | east of Osterode into the Söse |
| Mouth Elevation: | ca. |
| Custom Label: | References |
The Ospenke is a left tributary of the Söse near Osterode in the Harz Mountains of central Germany in the state of Lower Saxony.
The Ospenke rises between the valleys of the Apenke and Eipenke, runs parallel to the latter and empties from the left into the Söse in the suburb of Scheerenberg.