| Osman Saleh | |
| Office: | Minister of Foreign Affairs of Eritrea |
| Term Start: | 18 April 2007 |
| Predecessor: | Mohamed Omer |
| Order1: | 1st |
| Office1: | Minister of Education |
| Term Start1: | 1993 |
| Term End1: | 18 April 2007 |
| Successor1: | Semere Russom |
| Birth Name: | Osman Saleh Mohammed |
| Party: | PFDJ |
Osman Saleh Mohammed is an Eritrean government minister. He served as the first minister of education following independence, serving in that position from 1993 to 2007. He has oversaw the transition from the revolutionary EPLF school system to a national education system.
In April 2007, he was chosen to serve as the minister of foreign affairs.[1]