| Osman Ghani Khan | |
| Native Name: | ওসমান গণি খান |
| Office: | Chairman of United Nations Board of Auditors |
| Termend: | 1982 |
| Termstart: | 1980 |
| Office1: | 2nd Comptroller and Auditor General (Bangladesh) |
| Predecessor1: | Fazle Kader Muhammad Abdul Baqui |
| Successor1: | A K Azizul Huq |
| Termend1: | 31 December 1982 |
| Termstart1: | 1 March 1976 |
| Office2: | Member of Parliament |
| Constituency2: | Pabna-2 |
| Term Start2: | 20 March 1991 |
| Term End2: | 30 March 1996 |
| Predecessor2: | Mokbul Hossain |
| Successor2: | AKM Salim Reza Habib |
| Office3: | State Minister of Public Administration |
| Primeminister3: | Khaleda Zia |
| Birth Date: | 1923 1, df=yes |
| Birth Place: | Bera, Pabna, Bengal Presidency, British India (now in Bangladesh) |
| Death Place: | Singapore |
| Party: | Bangladesh Nationalist Party |
| Relations: | Nurul Alam Khan (Brother) |
| Alma Mater: | University of Calcutta |
| Education: | MA (economics) |
| Nationality: | Bangladeshi |
Osman Ghani Khan (1923-2000) was the former chairman of the United Nations Board of Auditors, a Bangladeshi civil servant, economist, Bangladesh Nationalist Party politician and the former Member of Parliament of Pabna-2.
Khan passed higher secondary from Government Saadat College in 1940. In 1943 and 1945, he received his B.A. (Honours) and M.A. in Economics from University of Calcutta, respectively.
Khan was appointed the first Defense secretary of Bangladesh in 1972.[1] He was appointed to the constitutional post Comptroller and Auditor General of Bangladesh at 1976. From 1980 to 1982, Khan was elected as chairman of the United Nations Board of Auditors.[2] After retirement, he was elected as a member of parliament from Pabna-2 as a Bangladesh Nationalist Party candidate in 1991.[3] He was appointed the Minister of Public Administration.[1]
Khan died on 26 April 2000 in Mount Elizabeth Hospital, Singapore.[1]