| Official Name: | Osikovo |
| Native Name: | Осиково |
| Settlement Type: | Village |
| Pushpin Map: | Bulgaria |
| Pushpin Label Position: | Location in Bulgaria |
| Subdivision Name: | Bulgaria |
| Subdivision Type1: | Province |
| Subdivision Name1: | Blagoevgrad Province |
| Subdivision Type2: | Municipality |
| Subdivision Name2: | Garmen |
| Leader Title: | Mayor |
| Leader Name: | Fikret Bayramov |
| Leader Party: | GERB |
| Area Total Km2: | 57.475 |
| Population As Of: | 15 December 2011[1] |
| Population Note: | GRAO |
| Population Total: | 500 |
| Timezone: | EET |
| Utc Offset: | +2 |
| Timezone Dst: | EEST |
| Utc Offset Dst: | +3 |
| Postal Code Type: | Postal Code |
| Postal Code: | 2965 |
| Area Code: | 07533 |
| Coordinates: | 41.7°N 70°W |
| Elevation M: | 1000 |
Osikovo is a mountainous village in Garmen Municipality, in Blagoevgrad Province, Bulgaria. It is situated in the Dabrash part of the Rhodope Mountains, 11 kilometers north-northwest of Garmen and 66 kilometers southeast of Blagoevgrad.
The village is mentioned in old Ottoman documents from 1636 as "a village with 65 non-Muslim households".[2] In 1900, Osikovo was described as a mixed village with 464 Bulgarian-Christian and 240 Bulgarian-Muslim people.[3] There is an old church "St Demetrius" (Bulgarian: Свети Димитър,), built in 1846 and an artistic monument of culture of local significance.[4]
Nowadays, Osikovo is a pomak village with no industrial subjects. People grow tobacco or go to work in other settlements or abroad. The village lies on the asphalt road between Ognyanovo, Blagoevgrad Province and Ribnovo after the village of Skrebatno, 15 kilometers from Ognyanovo. There are no health care or educational institutions in the village.
Osikovo Ridge on Graham Land, Antarctica is named after the village.