Oreobates saxatilis, also known as Tarapoto big-headed frog, is a species of frog in the family Strabomantidae. It is endemic to Peru and known from near its type locality near Tarapoto (San Martín Province) as well as from the Río Tambo District in the Satipo Province, Panguana in the Puerto Inca Province, and Río Kimbiri in the La Convención Province.
Oreobates saxatilis are large-sized among the Oreobates species; adults measure 45mm50mm in snout–vent length. The head is large and wider than long; the snout is short. The tympanum is distinct; the supra-tympanic fold is weak and short. The fingers and toes are long and slender and have no lateral fringes nor keels. Skin is granular, with round keratinized granules and small (only some slightly enlarged), sparse, low, flat warts. The venter is smooth. The dorsum is greyish brown with darker brown markings. The belly is immaculate.
The species was originally known from lowland tropical forest as well as from rocky streambeds in ravines on mountain slopes at elevations of 360m–600mm (1,180feet–2,000feetm) above sea level, although further sampling has extended its altitudinal range to 233m–1086mm (764feet–3,563feetm). In 2018 it was assessed as "Least Concern" by the International Union for Conservation of Nature (IUCN).