| State: | OR |
| Type: | OR |
| Route: | 74 |
| Map Custom: | yes |
| Map Notes: | Route 74 highlighted in red |
| Length Mi: | 85.09 |
| Direction A: | West |
| Terminus A: | in Heppner Junction |
| Junction: | in Lexington in Heppner |
| Direction B: | East |
| Terminus B: | in Nye |
| Previous Type: | OR |
| Previous Route: | 70 |
| Next Type: | OR |
| Next Route: | 78 |
Oregon Route 74 is an Oregon, U.S. state highway running from Interstate 84 in Gilliam County to U.S. Route 395 in Umatilla County. OR 74 is known as the Heppner Highway No. 52 (see Oregon highways and routes). It is 83.05miles long and runs east - west.
Part of OR 74 is included in the Blue Mountain Scenic Byway.
OR 74 begins at an intersection with I-84 approximately 11miles east of Arlington at Heppner Junction. It heads southeast through Ione to Lexington. At Lexington, OR 74 overlaps OR 207 and continues southeast to Heppner. The concurrency ends at Heppner, and OR 74 continues east to Nye, ending at an intersection with US 395.