| State: | OR |
| Type: | OR |
| Route: | 52 |
| Map Custom: | yes |
| Map Notes: | Route 52 highlighted in red |
| Length Mi: | 1.65 |
| Length Round: | 2 |
| Direction A: | West |
| Terminus A: | at Payette Junction |
| Direction B: | East |
| Terminus B: | near Payette, Idaho |
| Established: | 1952 |
| Previous Type: | OR |
| Previous Route: | 51 |
| Next Type: | OR |
| Next Route: | 53 |
Oregon Route 52 (OR 52) is a very short Oregon state highway that runs from OR 201 at Payette Junction, Oregon, to the Snake River (the Idaho state line) at Payette, Idaho. It is a continuation of ID 52 and was once signed as Oregon Route 90. OR 52 consists of the Payette Spur No. 492 (see Oregon highways and routes).
OR 52 begins at an intersection with OR 201 at Payette Junction and continues south to the Idaho state line at Payette, Idaho, where it continues as ID 52.
The Payette Spur was designated OR 90 in 1932 and renumbered OR 52 in 1952.