Ophiolysin Explained

Ophiolysin
Ec Number:3.4.24.51

Ophiolysin (Ophiophagus metalloendopeptidase) is an enzyme.[1] This enzyme catalyses the following chemical reaction

Cleavage of Asn3-Gln, Gln4-His, His10-Leu, Ala14-Leu, and Tyr16-Leu in insulin B chain

This endopeptidase is present in the venom of the king cobra (Ophiophagus hannah)

Notes and References

  1. Yamakawa Y, Omori-Satoh T . A protease in the venom of king cobra (Ophiophagus hannah): purification, characterization and substrate specificity on oxidized insulin B-chain . Toxicon . 26 . 12 . 1145–55 . 1988 . 3070833 . 10.1016/0041-0101(88)90299-1 .

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