Opalski cells explained

An Opalski cell is a large (up to 35 μm in diameter) altered glial cell, originated from degenerating astrocytes, with small, eccentric, pyknotic, densely staining nuclei (single or multiple) displaced to the periphery, and fine granular cytoplasm, found in the cortical and subcortical regions (basal ganglia and thalamus) of the brains of people with Wilson disease and acquired hepatolenticular degeneration. Opalski cells was described by Adam Opalski, Polish neurologist and neuropathologist.[1] [2] [3] [4] [5]

Notes and References

  1. Web site: Jerzy Kulczycki. Professor Adam Opalski (1897-1963) – neurologist and neuropathologist. Neurologia i Neurochirurgia Polska 2009; 43, 4 . 2013-02-21 . https://web.archive.org/web/20131029191420/http://www.termedia.pl/Czasopismo/-15/pdf-13090-2?filename=Professor%20Adam%20Opalski%20-%20Angielski.pdf . 2013-10-29 . dead .
  2. 10.1007/BF02865108 . Über eine besondere Art von Gliazellen bei der Wilson-Pseudosklerosegruppe . 1930 . Opalski . A. . Zeitschrift für die gesamte Neurologie und Psychiatrie . 124 . 420 .
  3. 10.1007/BF00691216 . Some remarks on the morphology and histochemistry of the so-called Opalski cells . 1965 . Mossakowski . M. J. . Acta Neuropathologica . 4 . 6 . 659–68 . 5886838.
  4. William Pryse-Phillips. Companion to Clinical Neurology. 2003
  5. Susan L. Bartolucci, Thomas Lathrop Stedman, Pat Forbis, CMT. Stedman's Medical Eponyms. 2005

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