| Official Name: | Opalipsovo |
| Native Name: | Опалипсово |
| Settlement Type: | Village |
| Pushpin Map: | Russia Vologda Oblast#Russia |
| Subdivision Type: | Country |
| Subdivision Name: | Russia |
| Subdivision Name1: | Vologda Oblast |
| Subdivision Name3: | Velikoustyugsky District |
| Subdivision Type4: | Municipality |
| Utc Offset1: | +3:00 |
| Coordinates: | 60.7167°N 57°W[1] |
Opalipsovo (Russian: Опалипсово) is a rural locality (a village) in Samotovinskoye Rural Settlement, Velikoustyugsky District, Vologda Oblast, Russia. The population was 52 as of 2002.[2]
Opalipsovo is located 9 km southwest of Veliky Ustyug (the district's administrative centre) by road. Osinovo is the nearest rural locality.[3]