Opaganib Explained

Opaganib (ABC294640) is a drug which acts as an inhibitor of the enzyme sphingosine kinase 2. It is under development as a potential treatment agent for several different kinds of cancer.[1] [2]

Notes and References

  1. Camp ER, Patterson LD, Kester M, Voelkel-Johnson C . Therapeutic implications of bioactive sphingolipids: A focus on colorectal cancer . Cancer Biology & Therapy . 18 . 9 . 640–650 . September 2017 . 28686076 . 10.1080/15384047.2017.1345396 . 5663409 .
  2. Lewis CS, Voelkel-Johnson C, Smith CD . Targeting Sphingosine Kinases for the Treatment of Cancer . Advances in Cancer Research . 2018 . 140 . 295–325 . 30060814 . 10.1016/bs.acr.2018.04.015 . 6447312 . 9780128142233 .

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