Oocyte maturation inhibitor explained
The oocyte maturation inhibitor (OMI) is an inhibitory factor created by follicular cells during a primary oocyte maturation. It is believed to be the reason why the oocyte remains for so long in the immature dictyate state of meiosis.[1]
Notes and References
- Channing CP, Liu CQ, Jones GS, Jones H . Decline of follicular oocyte maturation inhibitor coincident with maturation and achievement of fertilizability of oocytes recovered at midcycle of gonadotropin-treated women . Proc. Natl. Acad. Sci. U.S.A. . 80 . 13 . 4184–8 . July 1983 . 6408644 . 394225 . 1983PNAS...80.4184C . 10.1073/pnas.80.13.4184. free .