This is a list of numbered roads in the City of Hamilton, Ontario, in the former Regional Municipality of Hamilton-Wentworth. After the amalgamation of the city and the region in 2001, most regional roads were de-numbered, leaving only a few arterial roads numbered, all of them (with the exception of HR 65) former provincial highways, numbered for continuity.
| Route | Local Name(s) | Northern/Western Terminus | Southern/Eastern Terminus | Settlements served | Additional Notes |
|---|---|---|---|---|---|
| Carman Road Dundas Street East Mountain Road Reids Mills Road | Harrisburg Road | Evans Road | Troy, Peters Corners, Clappison's Corners, Waterdown | Formerly Highway 5. Interrupted from Peters Corners to Clappison's Corners by becoming a still-extant section of Highway 5. | |
| Highway No. 8 King Street Cootes Drive Main Street Queenston Road | Niagara Region limits | Peters Corners, Christies Corners, Greensville, Dundas, Hamilton, Stoney Creek, Fruitland, Winona | Formerly Highway 8 | ||
| Centennial Parkway Rymal Road | Niagara Region limits | Stoney Creek, Elfrida | |||
| Copetown Road | Highway 5 | Highway 403 | Peters Corners, Copetown, Summit | ||
| Regional Road 56 | Regional Road 20 | Haldimand County limits | Elfrida, Binbrook | Formerly Highway 56 | |
| Trinity Road Sawmill Road Carluke Road White Church Road Binbrook Road | Highway 403 | Westbrook Road | Trinity, Carluke, Binbrook | ||
| Old Beverly Road | Waterloo County limits | Valens | Formerly Highway 97 | ||
| Governors Road | Bethel Church Road | Regional Road 8 | Lynden, Copetown, Dundas | ||