| One Enterprise Center | |
| Former Names: | Florida National Bank Building, First Union Bank Tower, Wachovia Bank Tower, Wells Fargo Tower |
| Location: | 225 Water Street Jacksonville, Florida |
| Coordinates: | 30.3257°N -81.6616°W |
| Map Type: | United States Jacksonville#USA Florida |
| Completion Date: | 1986 |
| Building Type: | Commercial Office |
| Roof: | 299feet |
| Floor Count: | 21 |
| Floor Area: | 317577square feet |
| Architect: | Clark Tribble Harris & Li Architects |
One Enterprise Center is a 299feet skyscraper in Jacksonville, Florida.[1] Located in the Northbank area of Downtown, tenants include Rayonier and CBRE Group. The building also shares a lobby with an adjacent Omni Hotel. The 21-floor structure was designed by Clark Tribble Harris & Li Architects and completed in 1986.[2]