Legal Status: | Investigational |
Cas Number: | 1928707-56-5 |
Pubchem: | 91885568 |
Unii: | T34SH2H9HI |
Synonyms: | F901318 |
Iupac Name: | 2-(1,5-Dimethyl-3-phenylpyrrol-2-yl)-N-[4-[4-(5-fluoropyrimidin-2-yl)piperazin-1-yl]phenyl]-2-oxoacetamide |
C: | 28 |
H: | 27 |
F: | 1 |
N: | 6 |
O: | 2 |
Olorofim (F901318) is an experimental antifungal drug being developed for invasive mold infections.[1] [2] If approved it would be a first-in-class medication (for the orotomide class). In 2023, the FDA decided not to approve the drug and to request more data about the safety of the drug.[3] Olorofim does not inhibit growth of Candida species.[2]