| Ojo de Agua Department | |
| Native Name Lang: | es |
| Settlement Type: | Department |
| Mapsize: | 180px |
| Subdivision Type: | Country |
| Subdivision Name: |  Argentina |
| Subdivision Type1: | Province |
| Subdivision Name1: | Santiago del Estero |
| Seat Type: | Capital |
| Seat: | Villa Ojo de Agua |
| Unit Pref: | Metric |
| Timezone1: | ART |
Ojo de Agua is a department of Argentina in Santiago del Estero Province. The capital city of the department is Villa Ojo de Agua.