| State: | OH |
| Type: | SR |
| Route: | 164 |
| Map: | OH 164 map.svg |
| Maint: | ODOT |
| Length Mi: | 63.57 |
| Length Round: | 2 |
| Length Ref: | [1] |
| Established: | 1923 |
| Direction A: | South |
| Terminus A: | near Leesville |
| Junction: |
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| Direction B: | North |
| Terminus B: | near Boardman |
| Counties: | Mahoning, Columbiana, Carroll, Jefferson |
| Previous Type: | SR |
| Previous Route: | 163 |
| Next Type: | SR |
| Next Route: | 165 |
State Route 164 (SR 164) is a state highway passing through four counties in east-central Ohio. The route runs in a general southwest to northeast fashion, and is signed north - south accordingly. The southern terminus is at an intersection with State Route 212 1miles south of Leesville, and the northern terminus is at Interstate 680 and Western Reserve Road on the Beaver and Boardman township boundary between North Lima and Boardman. The southern part of the route serves more rural areas while it makes its way through larger villages and cities toward its northern end.
SR 164 was commissioned in 1923, routed from Salineville to Youngstown. The highway was rerouted from North Lima to Youngstown along previous Route 7, in 1926. In 1937 the route was extended south to SR 43 in Amsterdam. The route was extended southeast to the current intersection at SR 212, south of Leesville, in 1938. Between 1977 and 1979 the northern terminus was relocated to the current interchange with I–680.