Ohio's 22nd senatorial district has historically been based in north central Ohio. It now consists of the counties of Medina, Ashland, Richland, and a portion of Holmes County. It encompasses Ohio House districts 2, 69 and 70. It has a Cook PVI of R+6. Its Ohio Senator is Republican Mark Romanchuk.
| Senator | Party | Term | Notes | ||
|---|---|---|---|---|---|
| Anthony O. Calabrese | Democrat | January 3, 1957 – December 31, 1980 | Calabrese lost reelection in 1980 to Ben Skall.[1] | ||
| Ben Skall | Republican | January 3, 1981 – May 20, 1984 | Skall was redistricted out of his district and resigned in 1984 prior to the expiration of his term. | ||
| Grace L. Drake | Republican | May 20, 1984 – December 31, 2000 | Drake was term-limited in 2000. | ||
| Ron Amstutz | Republican | January 3, 2001 – December 31, 2008 | Amstutz was term-limited in 2008. | ||
| Bob Gibbs | Republican | January 5, 2009 – December 31, 2010 | Gibbs resigned in 2010 after winning election to the United States Congress. | ||
| Larry Obhof | Republican | February 2, 2011 – December 31, 2020 | Obhof was term-limited in 2020. | ||
| Mark Romanchuk | Republican | January 4, 2021 – present | Incumbent |