Pogosta disease | |
Synonyms: | Karelian fever, Ockelbo disease |
Field: | Infectious disease |
Pogosta disease is a viral disease.[1] [2] The symptoms of the disease usually include rash, as well as mild fever and other flu-like symptoms; in most cases the symptoms last less than 5 days. However, in some cases, the patients develop a painful arthritis. There are no known chemical agents available to treat the disease.[3]
It has long been suspected that the disease is caused by a Sindbis-like virus, a positive-stranded RNA virus belonging to the Alphavirus genus and family Togaviridae.[1] In 2002 a strain of Sindbis was isolated from patients during an outbreak of the Pogosta disease in Finland, confirming the hypothesis.[3]
There is currently no treatment available.
This disease is mainly found in the Eastern parts of Finland; the disease was first detected in 1974 in the old parish village of Ilomantsi, sometimes called Pogosta.[4] A typical Pogosta disease patient is a middle-aged person who has been infected through a mosquito bite while picking berries in the autumn. The prevalence of the disease is about 100 diagnosed cases every year, with larger outbreaks occurring in 7-year intervals.[3]
It is also known as Karelian fever and Ockelbo disease. The names are derived from the words Pogosta, Karelia and Ockelbo.