Ochotona spanglei is an extinct species of pika (mammal in the family Ochotonidae), known from Late Miocene - Early Pliocene fossil from Oregon (USA). Fossils were also found in Nebraska referred to as Ochotona cf. spanglei.
Ochotona spanglei is the earliest known pika, which inhabited North America. Pika came at the Miocene-Pliocene boundary from Eurasia. Extinction of O. spanglei was followed by an approximately three-million-year-long gap in the known North American pikas record.