ORMDL1 explained

ORMDL sphingolipid biosynthesis regulator 1 is a protein that in humans is encoded by the ORMDL1 gene.^[1]

Further reading

• Araki W, Takahashi-Sasaki N, Chui DH, Saito S, Takeda K, Shirotani K, Takahashi K, Murayama KS, Kametani F, Shiraishi H, Komano H, Tabira T . A family of membrane proteins associated with presenilin expression and gamma-secretase function . FASEB J. . 22 . 3 . 819–27 . 2008 . 17928364 . 10.1096/fj.07-9072com . free . 3855661.
• Siow DL, Wattenberg BW . Mammalian ORMDL proteins mediate the feedback response in ceramide biosynthesis . J. Biol. Chem. . 287 . 48 . 40198–204 . 2012 . 23066021 . 3504734 . 10.1074/jbc.C112.404012 . free.
• Gupta SD, Gable K, Alexaki A, Chandris P, Proia RL, Dunn TM, Harmon JM . Expression of the ORMDLS, modulators of serine palmitoyltransferase, is regulated by sphingolipids in mammalian cells . J. Biol. Chem. . 290 . 1 . 90–8 . 2015 . 25395622 . 4281770 . 10.1074/jbc.M114.588236 . free.

Notes and References

1. Web site: Entrez Gene: ORMDL sphingolipid biosynthesis regulator 1. 2018-01-09.