OR7A5 explained

Olfactory receptor 7A5 is a protein that in humans is encoded by the OR7A5 gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Gerhard DS . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–2127 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . vanc. Wagner L . Feingold EA . 3 . Shenmen . CM . Grouse . LH . Schuler . G . Klein . SL . Old . S . Rasooly . R .
• Grimwood J . The DNA sequence and biology of human chromosome 19 . Nature . 428 . 6982 . 529–535 . 2004 . 15057824 . 10.1038/nature02399 . vanc. Gordon LA . Olsen A . 3 . Terry . Astrid . Schmutz . Jeremy . Lamerdin . Jane . Hellsten . Uffe . Goodstein . David . Couronne . Olivier . 2004Natur.428..529G . free .
• Malnic B, Godfrey PA, Buck LB . The human olfactory receptor gene family . Proc. Natl. Acad. Sci. U.S.A. . 101 . 8 . 2584–2589 . 2004 . 14983052 . 10.1073/pnas.0307882100 . 356993 . 2004PNAS..101.2584M . free .
• Strausberg RL . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–16903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . vanc. Feingold EA . Grouse LH . 3 . Derge . JG . Klausner . RD . Collins . FS . Wagner . L . Shenmen . CM . Schuler . GD . 2002PNAS...9916899M . free .
• Fuchs T . DEFOG: a practical scheme for deciphering families of genes . Genomics . 80 . 3 . 295–302 . 2003 . 12213199 . 10.1006/geno.2002.6830 . vanc. Malecova B . Linhart C . 3 . Sharan . Roded . Khen . Miriam . Herwig . Ralf . Shmulevich . Dmitry . Elkon . Rani . Steinfath . Matthias .
• Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M . Molecular cloning and chromosomal mapping of olfactory receptor genes expressed in the male germ line: evidence for their wide distribution in the human genome . Biochem. Biophys. Res. Commun. . 237 . 2 . 283–287 . 1997 . 9268701 . 10.1006/bbrc.1997.7043 .
• Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M . Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species . Genomics . 39 . 3 . 239–246 . 1997 . 9119360 . 10.1006/geno.1996.4490 .
• Parmentier M . Expression of members of the putative olfactory receptor gene family in mammalian germ cells . Nature . 355 . 6359 . 453–455 . 1992 . 1370859 . 10.1038/355453a0 . vanc. Libert F . Schurmans S . 3 . Schiffmann . Serge . Lefort . Anne . Eggerickx . Dominique . Ledent . Catherine . Mollereau . Catherine . Gérard . Catherine . 1992Natur.355..453P . 43926 .

Notes and References

1. Web site: Entrez Gene: OR7A5 olfactory receptor, family 7, subfamily A, member 5.