OR5F1 explained
Olfactory receptor 5F1 is a protein that in humans is encoded by the OR5F1 gene.[1] [2]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
See also
Further reading
- Fuchs T . DEFOG: a practical scheme for deciphering families of genes . Genomics . 80 . 3 . 295–302 . 2003 . 12213199 . 10.1006/geno.2002.6830 . vanc. Malecova B . Linhart C . 3 . Sharan . Roded . Khen . Miriam . Herwig . Ralf . Shmulevich . Dmitry . Elkon . Rani . Steinfath . Matthias . 10.1.1.135.3652 .
- Strausberg RL . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . vanc. Feingold EA . Grouse LH . 3 . Derge . JG . Klausner . RD . Collins . FS . Wagner . L . Shenmen . CM . Schuler . GD . 2002PNAS...9916899M . free .
- Malnic B, Godfrey PA, Buck LB . The human olfactory receptor gene family . Proc. Natl. Acad. Sci. U.S.A. . 101 . 8 . 2584–9 . 2004 . 14983052 . 10.1073/pnas.0307882100 . 356993 . 2004PNAS..101.2584M . free .
Notes and References
- Buettner JA, Glusman G, Ben-Arie N, Ramos P, Lancet D, Evans GA . Organization and evolution of olfactory receptor genes on human chromosome 11 . Genomics . 53 . 1 . 56–68 . Dec 1998 . 9787077 . 10.1006/geno.1998.5422 .
- Web site: Entrez Gene: OR5F1 olfactory receptor, family 5, subfamily F, member 1.
