OR52A1 explained

Olfactory receptor 52A1 is a protein that in humans is encoded by the OR52A1 gene.^{[1] [2]}

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[3]

See also

• Olfactory receptor

Further reading

• Bulger M, Bender MA, van Doorninck JH, etal . Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. . Proc. Natl. Acad. Sci. U.S.A. . 97 . 26 . 14560–5 . 2001 . 11121057 . 10.1073/pnas.97.26.14560 . 18958 . free .
• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Malnic B, Godfrey PA, Buck LB . The human olfactory receptor gene family. . Proc. Natl. Acad. Sci. U.S.A. . 101 . 8 . 2584–9 . 2004 . 14983052 . 10.1073/pnas.0307882100 . 356993 . 2004PNAS..101.2584M . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .

Notes and References

1. Feingold EA, Penny LA, Nienhuis AW, Forget BG . An olfactory receptor gene is located in the extended human beta-globin gene cluster and is expressed in erythroid cells . Genomics . 61 . 1 . 15–23 . Nov 1999 . 10512676 . 10.1006/geno.1999.5935 . free .
2. Web site: Entrez Gene: OR52A1 olfactory receptor, family 52, subfamily A, member 1.
3. Web site: Entrez Gene: OR52A1 olfactory receptor, family 52, subfamily A, member 1.