OR51M1 explained
Olfactory receptor 51M1 is a protein that in humans is encoded by the OR51M1 gene.[1]
Function
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals.[2] The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
See also
Further reading
- Bulger M, van Doorninck JH, Saitoh N, etal . Conservation of sequence and structure flanking the mouse and human beta-globin loci: the beta-globin genes are embedded within an array of odorant receptor genes. . Proc. Natl. Acad. Sci. U.S.A. . 96 . 9 . 5129–34 . 1999 . 10220430 . 10.1073/pnas.96.9.5129 . 21828 . 1999PNAS...96.5129B . free .
- Bulger M, Bender MA, van Doorninck JH, etal . Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. . Proc. Natl. Acad. Sci. U.S.A. . 97 . 26 . 14560–5 . 2001 . 11121057 . 10.1073/pnas.97.26.14560 . 18958 . free . 2000PNAS...9714560B .
- Malnic B, Godfrey PA, Buck LB . The human olfactory receptor gene family. . Proc. Natl. Acad. Sci. U.S.A. . 101 . 8 . 2584–9 . 2004 . 14983052 . 10.1073/pnas.0307882100 . 356993 . 2004PNAS..101.2584M . free .
Notes and References
- Web site: Entrez Gene: OR51M1 olfactory receptor, family 51, subfamily M, member 1.
- Knape K, Beyer A, Stary A, Buchbauer G, Wolschann P . Genomics of selected human odorant receptors . Chemical Monthly . 2008 . 139 . 12 . 1537–1544 . 10.1007/s00706-008-0957-6 . free .
