OR4D2 explained
Olfactory receptor 4D2 is a protein that in humans is encoded by the OR4D2 gene.[1]
Function
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[2]
See also
Further reading
- Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R . DEFOG: a practical scheme for deciphering families of genes . Genomics . 80 . 3 . 295–302 . September 2002 . 12213199 . 10.1006/geno.2002.6830 . 10.1.1.135.3652 .
- Malnic B, Godfrey PA, Buck LB . The human olfactory receptor gene family . Proceedings of the National Academy of Sciences of the United States of America . 101 . 8 . 2584–9 . February 2004 . 14983052 . 356993 . 10.1073/pnas.0307882100 . 2004PNAS..101.2584M . free .
Notes and References
- Web site: Entrez Gene: OR4D2 olfactory receptor, family 4, subfamily D, member 2.
- Web site: Entrez Gene: OR4D2 olfactory receptor, family 4, subfamily D, member 2.