OR2M7 explained

Olfactory receptor 2M7 is a protein that in humans is encoded by the OR2M7 gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[2]

Ligands

Agonists include:^[3]

• (-)-Citronellol
• Geraniol

See also

• Olfactory receptor

Further reading

• Malnic B, Godfrey PA, Buck LB . The human olfactory receptor gene family. . Proc. Natl. Acad. Sci. U.S.A. . 101 . 8 . 2584–9 . 2004 . 14983052 . 10.1073/pnas.0307882100 . 356993 . 2004PNAS..101.2584M . free .
• Gregory SG, Barlow KF, McLay KE, etal . The DNA sequence and biological annotation of human chromosome 1. . Nature . 441 . 7091 . 315–21 . 2006 . 16710414 . 10.1038/nature04727 . 2006Natur.441..315G . free .

Notes and References

1. Web site: Entrez Gene: OR2M7 olfactory receptor, family 2, subfamily M, member 7.
2. Web site: Entrez Gene: OR2M7 olfactory receptor, family 2, subfamily M, member 7.
3. Saito H, Chi Q, Zhuang H, Matsunami H, Mainland JD . Odor coding by a Mammalian receptor repertoire . Science Signaling . 2 . 60 . ra9 . March 2009 . 19261596 . 2774247 . 10.1126/scisignal.2000016 .