OR2M4 explained
Olfactory receptor 2M4 is a protein that in humans is encoded by the OR2M4 gene.[1] [2] [3]
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]
See also
Further reading
- Fuchs T, Malecova B, Linhart C, etal . DEFOG: a practical scheme for deciphering families of genes. . Genomics . 80 . 3 . 295–302 . 2003 . 12213199 . 10.1006/geno.2002.6830 . 10.1.1.135.3652 .
- Malnic B, Godfrey PA, Buck LB . The human olfactory receptor gene family. . Proc. Natl. Acad. Sci. U.S.A. . 101 . 8 . 2584–9 . 2004 . 14983052 . 10.1073/pnas.0307882100 . 356993 . 2004PNAS..101.2584M . free .
- Gregory SG, Barlow KF, McLay KE, etal . The DNA sequence and biological annotation of human chromosome 1. . Nature . 441 . 7091 . 315–21 . 2006 . 16710414 . 10.1038/nature04727 . 2006Natur.441..315G . free .
Notes and References
- Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J. Expression of members of the putative olfactory receptor gene family in mammalian germ cells . Nature . 355 . 6359 . 453–5 . Mar 1992 . 1370859 . 10.1038/355453a0 . 1992Natur.355..453P . 43926 . etal.
- Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M . Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species . Genomics . 39 . 3 . 239–46 . Apr 1997 . 9119360 . 10.1006/geno.1996.4490 .
- Web site: Entrez Gene: OR2M4 olfactory receptor, family 2, subfamily M, member 4.
- Web site: Entrez Gene: OR2M4 olfactory receptor, family 2, subfamily M, member 4.