OR2K2 explained

Olfactory receptor 2K2 is a protein that in humans is encoded by the OR2K2 gene.^{[1] [2] [3]}

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[4]

See also

• Olfactory receptor

Further reading

• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . free . 2002PNAS...9916899M .
• Malnic B, Godfrey PA, Buck LB . The human olfactory receptor gene family. . Proc. Natl. Acad. Sci. U.S.A. . 101 . 8 . 2584–9 . 2004 . 14983052 . 10.1073/pnas.0307882100 . 356993 . 2004PNAS..101.2584M . free .
• Humphray SJ, Oliver K, Hunt AR, etal . DNA sequence and analysis of human chromosome 9. . Nature . 429 . 6990 . 369–74 . 2004 . 15164053 . 10.1038/nature02465 . 2734081 . 2004Natur.429..369H .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .

Notes and References

1. Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J. Expression of members of the putative olfactory receptor gene family in mammalian germ cells . Nature . 355 . 6359 . 453–5 . Mar 1992 . 1370859 . 10.1038/355453a0 . 1992Natur.355..453P . 43926 . etal.
2. Aloni R, Olender T, Lancet D . Ancient genomic architecture for mammalian olfactory receptor clusters . Genome Biol . 7 . 10 . R88 . Jan 2007 . 17010214 . 1794568 . 10.1186/gb-2006-7-10-r88 . free .
3. Web site: Entrez Gene: OR2K2 olfactory receptor, family 2, subfamily K, member 2.
4. Web site: Entrez Gene: OR2K2 olfactory receptor, family 2, subfamily K, member 2.