OR2H1 explained

Olfactory receptor 2H1 is a protein that in humans is encoded by the OR2H1 gene.^[1]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[2]

See also

• Olfactory receptor

Further reading

• Strausberg RL, Feingold EA, Grouse LH, etal . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . free .
• Volz A, Ehlers A, Younger R, etal . Complex transcription and splicing of odorant receptor genes. . J. Biol. Chem. . 278 . 22 . 19691–701 . 2003 . 12637542 . 10.1074/jbc.M212424200 . free .
• Mungall AJ, Palmer SA, Sims SK, etal . The DNA sequence and analysis of human chromosome 6. . Nature . 425 . 6960 . 805–11 . 2003 . 14574404 . 10.1038/nature02055 . 2003Natur.425..805M . free .
• Malnic B, Godfrey PA, Buck LB . The human olfactory receptor gene family. . Proc. Natl. Acad. Sci. U.S.A. . 101 . 8 . 2584–9 . 2004 . 14983052 . 10.1073/pnas.0307882100 . 356993 . 2004PNAS..101.2584M . free .
• Gerhard DS, Wagner L, Feingold EA, etal . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 .
• Santos PS, Kellermann T, Uchanska-Ziegler B, etal . Genomic architecture of MHC-linked odorant receptor gene repertoires among 16 vertebrate species. . Immunogenetics . 62 . 9 . 569–84 . 2010 . 20680261 . 10.1007/s00251-010-0468-6 . 23003444 .

Notes and References

1. Web site: Entrez Gene: OR2H1 olfactory receptor, family 2, subfamily H, member 1.
2. Web site: Entrez Gene: OR2H1 olfactory receptor, family 2, subfamily H, member 1.